Standards library

Official standards behind every STAINIC form

199 official documents and guidelines - ISO, ASTM, OECD, ISTA, WOAH, EPPO, pharmacopoeias, EU law and clinical societies - mapped to the stains and methods that follow them.

Official documentBest practice (no single official standard)

Agriculture soil microbiology & apiculture 7 documents
Animal feed & pet food ingredient microscopy 1 documents
Aquaculture & fisheries diagnostics 2 documents
Chemical & analytical laboratories 8 documents
Construction materials & civil engineering 11 documents
Cosmetics & personal care 10 documents
Cultural heritage conservation & security documents 6 documents
Education biosafety & hygiene monitoring 11 documents
Environmental water wastewater & soil testing 24 documents
Food dairy beverages brewing & honey 27 documents
Forensic science & legal investigation 6 documents
Human (Clinical) 66 documents
  • 2017 International Consensus on ANCA testing (Bossuyt et al.) - antigen-specific immunoassay first, IIF supplementary

  • ACR synovial fluid classes; EULAR gout 2016 and CPPD 2011 (compensated polarised light microscopy)

  • ASCO/CAP ER & PR testing guideline (2020); ASCO/CAP HER2 guideline (2018, 2023 update incl. HER2-low/ultralow); International Ki-67 in Breast Cancer Working Group (2021); St Gallen surrogate subtypes

  • ASM / CLSI M54 - direct microscopy for fungi

  • ASM Clinical Microbiology Procedures Handbook; WHO STI laboratory manual (2023) - vaginal wet mount, Amsel criteria

  • ASM Clinical Virology Manual; CLSI M41 (Viral culture); WHO Laboratory Biosafety Manual (4th ed.)

  • ASM Manual of Clinical Microbiology; CDC STI Treatment Guidelines 2021 (confirm by NAAT); Tzanck smear is not type-specific

  • ASM Manual of Clinical Microbiology; EBV serological profile interpretation (VCA, EA, EBNA)

  • ASM Microbe Library standard protocol

  • Bancroft's - epithelial mucin & Cryptococcus capsule

  • Bancroft's Theory & Practice of Histological Techniques; IDSA fungal guidance

  • CAP Cancer Protocols / ICCR datasets; WHO Classification of Tumours (5th ed.)

  • CDC DPDx / ASM - modified acid-fast for coccidian parasites & Nocardia

  • CLSI H44-A2 / ICSH supravital reticulocyte counting

  • CLSI M35-A2 / ASM Clinical Microbiology Procedures; Nugent 1991 scoring

  • CLSI M54 (2nd ed., 2021) fungal direct microscopy; ASM Clinical Microbiology Procedures Handbook; IDSA / ESCMID-ECMM fungal guidelines

  • EADV S2k guideline on bullous pemphigoid (2022); epidermal (roof) vs dermal (floor) binding

  • EADV S2k guideline on pemphigus (2020) and bullous pemphigoid (2022); perilesional biopsy in Michel's medium

  • ERS guideline for diagnosis of primary ciliary dyskinesia (2017); BEAT-PCD international consensus on ciliary TEM (Shoemark et al., 2020)

  • ESMO Clinical Practice Guideline - Cancer of Unknown Primary (2023); NCCN Occult Primary; ICCR datasets; CAP cancer protocols

  • ESPGHAN 2020 coeliac disease guideline; ACG Clinical Guideline: Coeliac Disease (2023); BSG guideline

  • EULAR/ACR 2019 SLE classification; highly specific confirmatory anti-dsDNA assay

  • For fluids without a dedicated reporting system (hydrocele, cyst, drain, nipple discharge): descriptive categories; cell block & ancillary studies per ICCR / CAP cytology protocols

  • Hazelton & Gelderblom, Emerg Infect Dis 2003 (EM for rapid viral diagnosis); Biel & Gelderblom, J Clin Virol; WHO Laboratory Biosafety Manual (4th ed.)

  • IAC Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology (2020); triple test (clinical, imaging, cytology); BI-RADS 5th ed.

  • IAIHG simplified criteria for autoimmune hepatitis (2008); EASL Clinical Practice Guidelines: autoimmune hepatitis (2015) and PBC (2017)

  • ICAP International Consensus on ANA Patterns (anapatterns.org); EULAR/ACR 2019 SLE criteria (ANA >=1:80); ACR position statement on ANA testing

  • ICSH 2008 bone marrow guideline; Gale iron grading; WHO MDS-RS criteria

  • ICSH 2014 recommendations for RBC morphology grading; CLSI H20-A2 differential

  • ICSH bone marrow specimen & report standards (2008); WHO 2022 / EUMNET reticulin (MF-0 to MF-3), collagen and osteosclerosis grading; IMWG 2014; WHO systemic mastocytosis criteria

  • ICSH guidelines for the standardisation of bone marrow specimens and reports (2008); WHO Haematolymphoid Tumours 5th ed. (2022); ICC 2022; IMWG 2014

  • ICSH integrated bone marrow report (2008); WHO Haematolymphoid Tumours 5th ed. (2022); ICC 2022; IMWG 2014

  • IDSA / ESCMID fungal histopathology; WHO Fungal Priority Pathogens

  • IDSA bacterial meningitis 2004; ESCMID 2016; age-specific CSF reference ranges; traumatic tap correction. No international CSF cytology category system - descriptive reporting

  • IDSA Cryptococcal disease guideline; WHO 2022 cryptococcal guidelines

  • Immuno-EM best practice (Griffiths; Tokuyasu cryosection method); LR White / Lowicryl embedding; antibody validation per IHC good practice

  • International System for Reporting Serous Fluid Cytopathology (ISRSFC 2020, IAC-ASC) - serous fluids only: pleural, peritoneal (ascitic / washing), pericardial; BTS pleural guideline 2023

  • ISA Nomenclature Committee / Bancroft's - polarized light apple-green birefringence

  • Larone's Medically Important Fungi (7th ed.) identification criteria

  • METAVIR / Ishak liver fibrosis staging; AASLD

  • Renal Pathology Society recommendations for renal biopsy EM; Reynolds lead citrate (1963); glutaraldehyde-osmium processing per ASM / RPS practice

  • Renal Pathology Society; ISN/RPS lupus nephritis classification (2018 revision); Oxford MEST-C for IgA nephropathy

  • The Bethesda System for Reporting Cervical Cytology, 3rd ed. (2014)

  • The Bethesda System for Reporting Thyroid Cytopathology, 3rd ed. (2023); ACR TI-RADS 2017

  • The Milan System for Reporting Salivary Gland Cytopathology, 2nd ed. (2023) - ASC / IAC; WHO Head & Neck Tumours (5th ed.)

  • The Paris System for Reporting Urinary Cytology, 2nd ed. (2022) - ASC / IAC

  • The Sydney System for the Performance, Classification and Reporting of Lymph Node FNA Cytopathology (IAC 2020); WHO Classification of Haematolymphoid Tumours (5th ed.)

  • Updated Sydney System for gastritis (1996); OLGA staging

  • WHO / European Consensus bone marrow fibrosis grading (MF-0 to MF-3)

  • WHO / NLEP - Ridley Bacteriological Index & Morphological Index

  • WHO / NTEP (RNTCP) AFB smear grading - IUATLD scale

  • WHO Basic Malaria Microscopy (2010) & Malaria Microscopy QA Manual v2; WHO LD body density

  • WHO Bench Aids for the Diagnosis of Intestinal Parasites (2019); CDC DPDx; ICMR SOP stool examination

  • WHO Classification of Haematolymphoid Tumours (5th ed.) - >=3% blast positivity

  • WHO Classification of Haematolymphoid Tumours, 5th ed. (2022); ICC 2022; Hans algorithm (2004) for DLBCL cell of origin

  • WHO Classification of Soft Tissue & Bone Tumours, 5th ed. (2020); WHO Skin Tumours, 5th ed.; CAP melanoma & soft tissue protocols

  • WHO Classification of Tumours / CAP; CMV, HSV, adenovirus, HPV and polyomavirus IHC or ISH confirmation per ASM and CAP practice

  • WHO HIV guidelines (advanced disease: CD4 <200 cells/uL); NACO India CD4 testing guidelines; CDC/ICSH single-platform counting

  • WHO Laboratory Manual for Diphtheria (2021)

  • WHO Laboratory Techniques in Rabies (5th ed., 2018); WHO Expert Consultation on Rabies TRS 1012 (2018)

  • WHO LED fluorescence microscopy grading (2011) / IUATLD

  • WHO Reporting System for Lung Cytopathology (IAC-IARC-WHO, 2022); ATS BAL cellular analysis 2012

  • WHO Reporting System for Pancreaticobiliary Cytopathology (IAC-IARC-WHO, 2022); WHO Digestive System Tumours (5th ed.)

  • WHO Reporting System for Soft Tissue Cytopathology (IAC-IARC-WHO, 2023); WHO Soft Tissue & Bone Tumours (5th ed.)

  • WHO-HAEM5 (2022); ICSH guidelines for bone marrow; Bain - Leukaemia Diagnosis (cytochemistry); FAB criteria (historical)

  • WHO-HAEM5 & ICC 2022 lineage assignment (incl. MPAL); EuroFlow ALOT/AML panels; ICSH-ICCS 2006 consensus

Materials science electronics & nondestructive testing 23 documents
Mining geology petroleum & coal 12 documents
Packaging & container integrity 2 documents
Pharmaceuticals biopharma cell therapies & medical devices 22 documents
Plant health seed testing & plant research 11 documents
Regulatory toxicology & chemical safety laboratories 12 documents
Shipping & ballast water treatment testing 3 documents
Textiles leather dyes & coatings 12 documents
Veterinary & animal health 13 documents
Wood pulp & paper 15 documents

STAINIC summarises the reporting elements of these documents; it does not reproduce them or certify compliance. Always use the current edition, the manufacturer's instructions and your validated SOP.

Guideline-backed stain reporting for every laboratory.

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Medical & Professional Disclaimer

Guideline content, scores, pattern hints, auto-drafted impressions and AI suggestions from voice or microscope photos are decision-support and educational aids. They can be wrong and do not replace the professional judgement of a qualified pathologist, microbiologist, veterinarian, analyst or examiner, who must review and sign every report.

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STAINIC is a laboratory reporting tool, not a treatment website. It does not diagnose, prescribe or recommend therapy to patients. Patients should discuss results with their treating doctor.

Standards & References

Each industry (non-human) method form shows an 'Official' badge with the document it follows (e.g. ISO, ASTM, OECD, ISTA, WOAH, EPPO, pharmacopoeias, EU regulations) or a 'Best practice' badge with a caution where no single official procedure was found. STAINIC summarises the reporting elements only; it does not reproduce, replace or certify compliance with those documents. Always use the current edition, the manufacturer's instructions for use and your validated SOP, and check local regulatory limits.

Supplier Links

Reagent and supplier links are provided for convenience. Ranking and badges reflect STAINIC's editorial assessment and partnerships, not regulatory approval or a guarantee of product quality, price or availability. Verify product suitability, certificates and local registration with the seller.

Legal

Stain grading follows published standards (CLSI, WHO, NTEP, ICSH, Bethesda, CAP, ISO, ASTM, OECD and others) that remain the property of their authors and publishers. OCR is approximate and must be checked. Provided "as is" without warranty; liability is limited to the extent permitted by law.

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